Rules of Protein-DNA Recognition: Computational and Experimental Advances

Videos from BIRS Workshop 18w5045

, Washington University in St. Louis
- 10:16
The Coming of the Golden Age
Watch video | Download video: 201806040914-Stormo.mp4 (333M)
, Columbia University
- 11:21
Protein DNA recognition by Hox-cofactors complexes
Watch video | Download video: 201806041050-Mann.mp4 (115M)
, Boston University
- 11:51
Gene regulatory network rewiring by disease variants and transcription factor isoforms
Watch video | Download video: 201806041125-FuxmanBass.mp4 (139M)
, Emory University
- 15:29
Distal substitutions alter conformational space to create new functions among paralogous transcription factors
Watch video | Download video: 201806041502-Ortlund.mp4 (133M)
, Boston University
- 16:00
Biophysical principles of PU.1 binding revealed by nextPBM
Watch video | Download video: 201806041537-Siggers.mp4 (107M)
, Universidad Nacional Autonoma de Mexico
- 16:56
Inter-tissue, interspecies comparisons of the transcription factor JUN in endothelial cells identify regulatory mechanisms associated with vascular disease
Watch video | Download video: 201806041632-MedinaRivera.mp4 (105M)
, Technion-Israel Institute of Technology
- 17:26
Revealing the role of dual DNA and RNA binding proteins in Human embryonic stem cells
Watch video | Download video: 201806041701-Mandel-Gutfreund.mp4 (124M)
, New York University, Langone Medical Center
- 17:58
Direct and indirect influences that adjacent C2H2 zinc fingers have on DNA-binding strategies
Watch video | Download video: 201806041734-Noyes.mp4 (98M)
, Brigham and Women's Hospital and Harvard Medical School
- 09:25
Novel mechanism of bispecificity in forkhead transcription factors
Watch video | Download video: 201806050910-Rogers.mp4 (58M)
, Rutgers University
- 10:00
Higher-order chromatin structure: The role of Mediator
Watch video | Download video: 201806050932-Morozov.mp4 (125M)
, Columbia University
- 10:19
Accurate and sensitive quantification of protein-DNA binding affinity
Watch video | Download video: 201806051007-Rastogi.mp4 (44M)
, Center for Genomic Sciences, UNAM
- 11:27
Microbial Conditions Ontology (MCO): an effort to standardize the annotation of experimental conditions in microbial data
Watch video | Download video: 201806051108-Tierrafria.mp4 (69M)
, Washington University
- 11:57
Integration of local and regional cis-regulatory information
Watch video | Download video: 201806051136-Cohen.mp4 (90M)
, University of Chicago
- 12:43
Mechanisms for the evolution of steroid receptor/DNA specificity using ancestral reconstruction and deep mutational scanning
Watch video | Download video: 201806051209-Thornton.mp4 (172M)
, UNAM
- 15:33
A global analysis of the distance to transcription initiation of binding sites in bacterial promoters
Watch video | Download video: 201806051505-Collado-Vides.mp4 (129M)
, Stanford University
- 16:11
Probing effects of flanking sequence via high-resolution measurements of millions of TF-DNA binding energies
Watch video | Download video: 201806051539-Fordyce.mp4 (174M)
, Cincinnati Children's Hospital
- 17:04
Transcription factors operate across disease loci, with EBNA2 implicated in autoimmunity
Watch video | Download video: 201806051637-Weirauch.mp4 (134M)
, Penn State
- 17:41
Transcription factor crosstalk during developmental differentiation
Watch video | Download video: 201806051712-Llinas.mp4 (123M)
, Princeton University
- 18:03
Transcriptional atlas of a proto-vertebrate
Watch video | Download video: 201806051747-Chen.mp4 (69M)
, University of Cambridge
- 09:29
Genome-wide analysis of protein-DNA interactions
Watch video | Download video: 201806060902-Taipale.mp4 (110M)
, EPFL
- 10:07
SMILE-seq-based analysis of DNA binding specificities of human KRAB zinc-finger proteins
Watch video | Download video: 201806060942-Deplancke.mp4 (113M)
, NYU
- 10:32
A protein-protein interaction of adjacent C2H2 zinc fingers controls binding geometry and the residues able to specify DNA targets
Watch video | Download video: 201806061019-Mueller.mp4 (53M)
, Columbia University
- 09:33
A unified approach for quantifying and interpreting DNA shape readout by transcription factors
Watch video | Download video: 201806070905-Bussemaker.mp4 (121M)
, University of Iowa
- 10:05
The effects of sequence and mismatches on Cas9 activity
Watch video | Download video: 201806070941-Pufall.mp4 (90M)
, Weizmann
- 10:41
Molecular principles for optimizing protein-DNA interactions
Watch video | Download video: 201806071009-Levy.mp4 (153M)
, University of Southern California
- 11:41
A tale of DNA shape analysis: a user manual and next steps
Watch video | Download video: 201806071112-Rohs.mp4 (115M)
, Boston University
- 12:16
DNA shape – intrinsic or induced?
Watch video | Download video: 201806071149-Tullius.mp4 (118M)
, NIH
- 12:47
Modified cytosine and DNA binding
Watch video | Download video: 201806071222-Vinson.mp4 (104M)
, UMass Medical School
- 15:23
The ENCODE Encyclopedia of candidate cis-regulatory elements and transcription factor binding sites
Watch video | Download video: 201806071503-Pratt.mp4 (71M)
, University of Puerto Rico - Rio Piedras
- 15:55
Combinatorial recognition of DNA by bZIP transcription factors
Watch video | Download video: 201806071529-Rodriguez-Martinez.mp4 (110M)
, Ben-Gurion University
- 17:04
Deep learning for protein-RNA interactions
Watch video | Download video: 201806071632-Orenstein.mp4 (143M)
, University of Pittsburgh -
- 17:47
Towards a zinc finger code for RNA recognition
Watch video | Download video: 201806071710-Camacho.mp4 (165M)