Schedule for: 23w5079 - The Mathematics of Microbial Evolution: Beyond the Limits of Classical Theory

Beginning on Sunday, January 8 and ending Friday January 13, 2023

All times in Banff, Alberta time, MST (UTC-7).

Sunday, January 8
16:00 - 17:30 Check-in begins at 16:00 on Sunday and is open 24 hours (Front Desk - Professional Development Centre)
17:30 - 19:30 Dinner
A buffet dinner is served daily between 5:30pm and 7:30pm in Vistas Dining Room, top floor of the Sally Borden Building.
(Vistas Dining Room)
20:00 - 22:00 Informal gathering (TCPL Foyer)
Monday, January 9
07:00 - 08:45 Breakfast
Breakfast is served daily between 7 and 9am in the Vistas Dining Room, the top floor of the Sally Borden Building.
(Vistas Dining Room)
08:45 - 09:00 Lindi Wahl: Introduction and Welcome by BIRS Staff
A brief introduction to BIRS with important logistical information, technology instruction, and opportunity for participants to ask questions.
(TCPL 201)
09:00 - 09:20 Overview of the workshop: themes, lightning talks, topic "pitches", breakout groups, mentoring opportunities. (On site)
09:20 - 09:30 Load lightning talks (short break) (On site)
09:30 - 09:35 Helen Alexander: Mutation rate variation; quantifying stress-induced mutagenesis (TCPL 201)
09:35 - 09:40 Angela McLaughlin: Impact of sampling on molecular clock rate inference (TCPL 201)
09:40 - 09:45 Danna Gifford: Antimicrobial resistance, mutidrug resistance evolution and mutators (TCPL 201)
09:45 - 09:50 Martin Guillemet: High mutation rates and transient dynamics of pathogen adaptation: life-history evolution or lethal mutagenesis? (TCPL 201)
09:50 - 10:05 Open discussion (On site)
10:05 - 10:10 Mojgan Ezadian: Quantitative estimates of selection bias in bacterial mutation accumulation experiments (TCPL 201)
10:10 - 10:15 Lindi Wahl: Mutation bias during adaptation (TCPL 201)
10:15 - 10:20 Philip Gerrish: Robust estimation of population movement parameters from tail probabilities of coalescence times (TCPL 201)
10:20 - 10:30 Open discussion (On site)
10:30 - 11:00 Coffee Break (TCPL Foyer)
11:00 - 11:10 Load lightning talks (On site)
11:10 - 11:15 Sylvain Gandon: Modelling the evolution of adaptive plasticity of viruses (TCPL 201)
11:15 - 11:20 Claudia Igler: Phenotypic flux as phage resistance mechanism (TCPL 201)
11:20 - 11:25 Diana Fusco: Noise as an evolutionary trait in bacteriophage populations (TCPL 201)
11:25 - 11:35 Open discussion (On site)
11:35 - 11:40 Alison Feder: Density as a driver of viral evolution (TCPL 201)
11:40 - 11:45 Christina Burch: New insights into the mechanistic connections between micro and macro-evolution (from phage and computational evolution experiments). (TCPL 201)
11:45 - 11:50 Roland Regoes: Experimental epidemiology with viruses (TCPL 201)
11:50 - 12:00 Open discussion (On site)
12:00 - 13:00 Lunch
Lunch is served daily between 11:30am and 1:30pm in the Vistas Dining Room, the top floor of the Sally Borden Building.
(Vistas Dining Room)
13:00 - 14:00 Guided Tour of The Banff Centre
Meet in the PDC front desk for a guided tour of The Banff Centre campus.
(PDC Front Desk)
14:00 - 14:20 Group Photo
Meet in foyer of TCPL to participate in the BIRS group photo. The photograph will be taken outdoors, so dress appropriately for the weather. Please don't be late, or you might not be in the official group photo!
(TCPL Foyer)
14:20 - 14:55 Alicia Calvo-Villamanan: Using CRISPRi to have an integrative understanding of plasmid-mediated antibiotic resistance and its evolution (TCPL 201)
14:55 - 15:30 Aleeza Gerstein: Evolution in static vs. cidal environments (TCPL 201)
15:30 - 16:00 Coffee Break (TCPL Foyer)
16:00 - 17:30 Pitches and discussion of breakout group topics (On site)
17:30 - 19:30 Dinner
A buffet dinner is served daily between 5:30pm and 7:30pm in Vistas Dining Room, top floor of the Sally Borden Building.
(Vistas Dining Room)
Tuesday, January 10
07:00 - 08:45 Breakfast
Breakfast is served daily between 7 and 9am in the Vistas Dining Room, the top floor of the Sally Borden Building.
(Vistas Dining Room)
08:45 - 09:00 Load lightning talks (On site)
09:00 - 09:05 Claude Loverdo: Gut bacteria: hydrodynamic flow, spatial structure, and evolution (TCPL 201)
09:05 - 09:10 Alyssa Henderson: Drivers of metabolic distribution in microbial communities (TCPL 201)
09:10 - 09:15 Nicola Mulberry: A nested model for pneumococcal population dynamics (TCPL 201)
09:15 - 09:30 Open discussion (On site)
09:30 - 09:35 Sebastian Bonhoeffer: Antibiotic resistance evolution and in vitro epidemiology (TCPL 201)
09:35 - 09:40 Sara Loo: A simulation framework for pathogen trait evolution at within- and between-host scales (TCPL 201)
09:40 - 09:45 David McLeod: Modelling the role of adaptive immunity in pathogen strain structure (TCPL 201)
09:45 - 10:00 Open discussion (On site)
10:00 - 10:05 Abdul-Rahman Bukari: Geographical and temporal clusters of Candida albicans infection strains (TCPL 201)
10:05 - 10:10 Ethan Levien: Phase transitions in evolution of transcription factor binding sites (TCPL 201)
10:10 - 10:15 Oana Carja: Topological puzzles in biology: how shape and structure shape a system's evolution (TCPL 201)
10:15 - 10:30 Open discussion (On site)
10:30 - 11:00 Coffee Break (TCPL Foyer)
11:00 - 11:30 Rok Krasovec: Density-associated mutation rate plasticity: Where microbial interactions meet mutations (TCPL 201)
11:30 - 12:00 Pitches & discussion of breakout group topics (On site)
12:00 - 13:30 Lunch
Lunch is served daily between 11:30am and 1:30pm in the Vistas Dining Room, the top floor of the Sally Borden Building.
(Vistas Dining Room)
13:30 - 13:45 Sign up for a breakout discussion group (On site)
13:45 - 15:00 Initial group discussions (On site)
15:00 - 15:30 Philip Gerrish: Estimating the rate of mutation to mutator phenotype in spatially-structured microbial populations (TCPL 201)
15:30 - 16:00 Coffee Break (TCPL Foyer)
16:00 - 16:30 Anna Selmecki: Antifungal drug concentration impacts the spectrum of adaptive mutations in Candida albicans (TCPL 201)
16:30 - 17:30 More discussion groups (potentially changing groups) (On site)
17:30 - 19:30 Dinner
A buffet dinner is served daily between 5:30pm and 7:30pm in Vistas Dining Room, top floor of the Sally Borden Building.
(Vistas Dining Room)
Wednesday, January 11
07:00 - 08:45 Breakfast
Breakfast is served daily between 7 and 9am in the Vistas Dining Room, the top floor of the Sally Borden Building.
(Vistas Dining Room)
08:45 - 09:00 Load talks (On site)
09:00 - 09:30 Rafael Peña Miller: Plasmid dynamics in polymicrobial communities (TCPL 201)
09:30 - 10:00 Hildegard Uecker: Evolutionary dynamics on multicopy replicons in bacteria (TCPL 201)
10:00 - 10:30 Sonja Lehtinen: Plasmids, polyploidy and positive frequency-dependence: why are some bacterial genes on the chromosome and others on plasmids? (TCPL 201)
10:30 - 11:00 Coffee Break (TCPL Foyer)
11:00 - 12:00 Report back from discussion groups (On site)
12:00 - 13:30 Lunch
Lunch is served daily between 11:30am and 1:30pm in the Vistas Dining Room, the top floor of the Sally Borden Building.
(Vistas Dining Room)
13:30 - 17:30 Free Afternoon (Banff National Park)
17:30 - 19:30 Dinner
A buffet dinner is served daily between 5:30pm and 7:30pm in Vistas Dining Room, top floor of the Sally Borden Building.
(Vistas Dining Room)
Thursday, January 12
07:00 - 08:45 Breakfast
Breakfast is served daily between 7 and 9am in the Vistas Dining Room, the top floor of the Sally Borden Building.
(Vistas Dining Room)
08:45 - 09:00 Load talks (On site)
09:00 - 09:30 Oskar Hallatschek: The role of jackpot events in coupling allele frequencies across space and time (in microbial & viral evolution) (TCPL 201)
09:30 - 10:00 Ailene MacPherson: Demography, Epidemiology, and Geography Determine Maintenance of Diversity under Red Queen Coevolution (TCPL 201)
10:00 - 10:30 Vincent Calvez: Large fluctuations in a simple quantitative genetics model of adaptation to a changing environment (TCPL 201)
10:30 - 11:00 Coffee Break (TCPL Foyer)
11:00 - 12:00 Discussion groups (potentially new topics) (On site)
12:00 - 13:30 Lunch
Lunch is served daily between 11:30am and 1:30pm in the Vistas Dining Room, the top floor of the Sally Borden Building.
(Vistas Dining Room)
13:30 - 15:00 Discussion groups (On site)
15:00 - 15:30 Daniel Weissman: SARS-CoV-2 evolution at the population and individual level (TCPL 201)
15:30 - 16:00 Coffee Break (TCPL Foyer)
16:00 - 16:30 Aude Bernheim (TCPL 201)
16:30 - 17:00 Bartlomiej Waclaw: Can simple models predict the evolution of antibiotic resistance? (TCPL 201)
17:30 - 19:30 Dinner
A buffet dinner is served daily between 5:30pm and 7:30pm in Vistas Dining Room, top floor of the Sally Borden Building.
(Vistas Dining Room)
Friday, January 13
07:00 - 08:45 Breakfast
Breakfast is served daily between 7 and 9am in the Vistas Dining Room, the top floor of the Sally Borden Building.
(Vistas Dining Room)
09:30 - 10:30 Report back from discussion groups, general/unstructured discussion (On site)
10:30 - 11:00 Coffee Break (TCPL Foyer)
10:30 - 11:00 Checkout by 11AM
5-day workshop participants are welcome to use BIRS facilities (TCPL ) until 3 pm on Friday, although participants are still required to checkout of the guest rooms by 11AM.
(Front Desk - Professional Development Centre)
11:00 - 11:30 wrap-up and survey (on-site)
12:00 - 13:30 Lunch from 11:30 to 13:30 (Vistas Dining Room)