Mathematical and Statistical Challenges in Bridging Model Development, Parameter Identification and Model Selection in the Biological Sciences (18w5144)

Organizers

Ruth Baker (University of Oxford)

(University of British Columbia)

(Queensland University of Technology)

Description

The Banff International Research Station will host the "Mathematical and Statistical Challenges in Bridging Model Development, Parameter Identification and Model Selection in the Biological Sciences" workshop from November 11th to November 16th, 2018.


Using mathematical and computational models to assist in the design and interpretation of biological experiments is becoming increasingly important in biotechnology and biomedical engineering research because, together with quantitative data, models allow for the effects of multiple interacting mechanisms to be explored in a rigorous framework. However, such models must be tested/validated and refined before they can be used to further understanding by making predictions that can be tested experimentally.


A key challenge for the future is to understand how to integrate multiplex biological data to develop models, identify model parameters, select between models that encode different hypotheses, and determine the best experiments for testing model-derived hypotheses. Novel mathematical, statistical and computational tools are needed to meet this challenge. They will enable the development of a standardised pipeline for the integration of quantitative experimental data with models so that we can accelerate progress in our understanding of complex biological systems. This workshop will bring together researchers specialist in using a range of mathematical and statistical techniques to share ideas and make progress towards tackling this challenge.



The Banff International Research Station for Mathematical Innovation and Discovery (BIRS) is a collaborative Canada-US-Mexico venture that provides an environment for creative interaction as well as the exchange of ideas, knowledge, and methods within the Mathematical Sciences, with related disciplines and with industry. The research station is located at The Banff Centre in Alberta and is supported by Canada's Natural Science and Engineering Research Council (NSERC), the U.S. National Science Foundation (NSF), Alberta's Advanced Education and Technology, and Mexico's Consejo Nacional de Ciencia y Tecnología (CONACYT).